Atropine is a competitive muscarinic antagonist, used to treat drug-induced bradycardia and poisoning by acetylcholinesterase inhibitors Organophosphate poisoning: Adult Dose = 1.2mg with further dosing every 2-3 mins, doubling the dose each time until there is drying of secretions. Paediatric dose = 50 micrograms/kg. Heart rate is not a useful endpoint due to tachycardia from […]
Used for both the acute or chronic overdose. Typically this is from the pharmaceutical agent digoxin. Other cardiac glycosides such as Oleander can be treated with digoxin immune fab.
Antivenom is widely used for Australian envenoming syndromes. Antivenoms are generally perceived, by both clinicians and the general public, as highly effective treatments. However, there is little evidence to support this widely held view, in fact, the weight of evidence suggests that some antivenoms are ineffective in clinical practice.
The bluebottle jellyfish is responsible for thousands of stings on Australian beaches each year. Clinical features include intense local pain and dermal erythema. Hot water immersion provides safe symptomatic relief. Unlike Physalia stings in other parts of the world, major systemic envenoming does not occur.
The box jellyfish is found in tropical Australian waters. Most stings are benign and respond to supportive measures. Severe envenoming has been associated with at least 67 deaths in Australia, the last 12 being children.
Last October, a report of death by loxoscelism was reported in Annals. It’s a sad story about a previously healthy 3 year old girl who was bitten by a witnessed brown recluse in Tennessee. She went to a rural ED, was evaluated and discharged. Only physical finding at that time was small red patch on […]
LITFL’s Joe Rotella speaks to Anselm Wong about GETUP! The Global Educational Toxicology Uniting Project supported by ACMT.
Expanding on my comments from the ALiEM Patwari Academy post on snakebites, here is some data behind neostigmine use in elapidae bites.