Difficulty weaning is an important ICU challenge. 20% to 30% of patients are difficult to wean from invasive mechanical ventilation
Non-invasive ventilation can be used as adjunct for weaning patients from mechanical ventilation
Numerous objective indices have been studied to predict failure of ventilator liberation or weaning. None of these indexes alone are sufficiently sensitive and specific to be useful in predicting the success of ventilation discontinuation in an individual patient.
Spontaneous breathing trials (SBT) are used to identify patients who are likely to fail liberation from mechanical ventilation