Mary Broadfoot Walker (1888 - 1974) was a Scottish physician. Mary Walker effect (1934); neostigmine and myasthenia gravis
A reversible acetylcholinesterase inhibitor useful in the treatment of central anticholinergic delirium that is not easily controlled by benzodiazepine sedation and there is high risk for aspiration and excessive sedation. Only for those patients who have an isolated anticholinergic agent toxicity (not the polypharmacy overdose).
Physostigmine: anticholinesterase; inhibition of anticholinesterase -> increase in cholinergic tone