Tag Regional Citrate Anticoagulation
CCC Critical Care compendium 340

Regional citrate anticoagulation

Regional Citrate Anticoagulation is the infusion of citrate into the blood circuit during renal replacement therapy (RRT) to chelate ionized Ca2+ forming calcium-citrate complexes, thus preventing coagulation of blood; calcium is required for the generation of thrombin (involved in the activation of factors II, IX and X)