Tag rTPA
CCC Critical Care compendium 340

Alteplase (rtPA)

Alteplase (rtPA): recombinant tissue plasminogen activator (rt-PA); thrombolytic; selectively binds to fibrin and converts plasminogen -> plasmin -> degradation of fibrin matrix

Busting the clotbusters (from SMACC 2013)

As revenge for an incident best left unmentioned, Chris Nickson of litfl.com handed me the poisoned chalice of speaking on tPA for stroke at SMACC 2013. This is the result. (Un)fortunately there is no actual video footage as I wasn’t…