Tag Tramadol

Tramadol toxicity

Tramadol in overdose would have the opiate toxidrome expected (sedation and respiratory depression) but it also can potentially cause seizures in doses >1.5 grams. Tramadol has also been associated with serotonin toxicity, rarely as a single agent but commonly with other co-ingested serotinergically active agents.
CCC Critical Care compendium 340


Tramadol: synthetic opioid of the aminocyclohexanol group; centrally acting opioid receptor agonist + more!