Out-Sleep the Competition: Part 1
Sleep as a Peak Performance State
Can you remember the last time you woke feeling sharp, clear, and fully charged—without caffeine or an alarm clock?
If you can’t, you’re not alone.
Two-thirds of adults in developed nations don’t get the 8 hours of sleep recommended by the World Health Organization.
We are the only species that willingly deprives ourselves of sleep with no benefit.
This isn’t resilience.
It’s sabotage.
Let me be clear:
Sleep is not rest.
It is a biological upgrade.
Sleep is an elite physiological state that improves every single domain of human function—mental, emotional, and physical.
And every hour you shave off, you blunt your potential.
Sleep isn’t optional.
It’s foundational.
The Truth About Sleep Deprivation
We glamorize burnout.
Wear fatigue like a badge of honour.
But the science is ruthless.
- <6 hours of sleep? Your risk of cancer spikes by 50%.
- One week of <6h sleep? You’re 200% more likely to have a heart attack.
- Pulling an all-nighter reduces learning and grades by 40%, even after 2 nights of recovery sleep.
- Want to feel dumb? Stay sleep deprived, a study of high school students found that those who slept less than 8 hours because they had to get up early for the school bus finished an entire grade level below their peers. Creating an ongoing debate about school start times.
- Chronic sleep loss leads to emotional volatility, memory loss, weight gain, infertility, stroke, depression, and yes—dementia.
It’s not just about how you feel.
It’s how your brain performs, your heart functions, your genes express, and your body repairs.
There is no system that sleep doesn’t touch.
And no hack that replaces it.
Fatal Fatigue
Can sleep deprivation kill you?
Yes. Directly.
There’s a rare genetic disease called Fatal Familial Insomnia where people simply lose the ability to sleep.
Within 18 months, they die. Every. Single. One.
More common? Microsleeps.
Tiny 2–3 second blackouts when the brain forcibly shuts down.
At highway speed, that’s enough to cross an intersection blind.
Every hour in the U.S., someone dies from drowsy driving—more than alcohol and drugs combined.
In medicine, aviation, and elite sport, fatigue isn’t fatigue.
It’s risk.
The Neuroscience of Sleep
Sleep isn’t one state. It’s a repeating cycle of phases, each with distinct brain activity and benefits.
You move through these phases every 90–110 minutes, cycling 4–6 times per night:
Stage 1 NREM (Light Sleep, ~5%)
- The transition zone. It’s a brief transition from wakefulness to sleep.
Low amplitude, mixed-frequency EEG. - Muscle tone drops. Eye movement slows.
- The brain begins to power down.
Stage 2 NREM (Light Sleep, ~50%)
- The largest portion of total sleep time in healthy adults (typically 45–55%)
- Characterized by sleep spindles and K-complexes—electrical bursts that help filter noise and consolidate memories.
- This is where motor memory (surgical skills, instruments, physical routines) begins encoding.
- Spindles transfer info from hippocampus → cortex.
Stage 3 NREM (Slow-Wave Sleep) (~20% – less in older adults)
- The deepest stage. Also called delta sleep.
- The brain emits slow, high-amplitude delta waves.
- This is when the glymphatic system activates, flushing out metabolic waste like amyloid beta (Alzheimer’s link).
- Deep NREM sleep also puts the brake on the sympathetic nervous system and averts hypertension and stroke. 1.5 billion people experiment with this every year though daylight savings. The next day, there is a spike in heart attacks.
- Immune function, physical healing, and growth hormone release peak here.
- Miss this stage, and you accelerate aging.
REM Sleep (~20–25%, increasing across the night in later sleep cycles)
- First REM episode is approximately 10 minutes, but the final REM episode (just before waking) can be up to 60 mins. That’s why sleeping a full 8 hours gives you more REM sleep.
- Brain activity resembles wakefulness—but the body is paralyzed.
- This is where you dream, process emotions (via amygdala-PFC remodelling), and integrate experiences.
- REM is crucial for creativity, problem-solving, and emotional intelligence.
- You make connections—between old memories, new input, and abstract ideas (recombining neural inputs).
Cut your sleep short, and you cut REM.
You lose resilience, innovation, and insight.
Sleep = Brain Cleaning, Memory Building, and Emotional Triage
- Awake: You receive information.
- NREM: You reflect, clean, and organize.
- REM: You rebuild, solve, and integrate.
Sleep is not passive. It’s a cognitive triage centre.
Think of it this way:
You learn during the day.
You understand during sleep.
Sleep Debt: The Hidden Killer
Pull one all-nighter, and your hippocampus—your brain’s inbox—shuts down.
You can’t form new memories. You might hear the words, read the slide, even nod—but nothing sticks.
Your brain is open… but not recording.
Now imagine sleeping 6 hours a night for 10 days.
You might think you’re functioning fine.
But your cognitive performance has dropped to the same level as being awake for 24 straight hours.
Sleep just 4 hours a night?
Your brain performs like you’ve pulled an all-nighter every day.
And here’s the kicker:
You won’t notice.
People consistently underestimate their own level of impairment.
Fatigue builds a false baseline—you forget what it feels like to be sharp, focused, creative, and emotionally stable.
Worse still?
Recovery is not immediate.
One good night of sleep doesn’t erase the deficit.
In studies, full cognitive restoration required three consecutive nights of proper sleep.
Sleep is not a buffer.
It’s a biological reset button—and if you don’t press it daily, your system clogs.
Sleep, Sex, Weight, and Immunity
Let’s be blunt.
If you’re sleeping less than 6 hours a night, here’s what happens:
Sex & Hormones
- Testosterone tanks—equivalent to aging 10–15 years.
- In one study, healthy men who slept 5 hours a night for a week had 29% lower sperm counts, smaller testes, and abnormal morphology.
- In women, FSH (follicle-stimulating hormone) drops, ovulation delays, and cycles become irregular.
- Shift workers have an 80% higher rate of infertility.
- Less than 8 hours of sleep? Increased risk of miscarriage.
Sleep isn’t just libido.
It’s reproductive viability.
Weight & Metabolism
- Sleep loss increases ghrelin (hunger hormone) and decreases leptin (satiety hormone).
- Result? You’ll eat 300–500 more calories per day.
- That’s 12–15 kg of weight gain per year from sleep loss alone.
- Sleep deprivation increases endocannabinoids—your brain literally gets the munchies.
- It also causes a loss of lean body mass during weight loss (muscle loss > fat loss).
- You make worse food choices, crave carbs, and lose prefrontal control over impulses.
And get this:
Just 4 hours of sleep per night for 6 nights can push a healthy adult into a prediabetic state.
Their cells become insulin resistant. Their blood sugar spikes.
This effect is reversible—but only with proper sleep.
Immunity & Cancer
- Sleep deprivation and the common cold. In one famous study, those who slept less than 7 hours for one week were 50% more likely to develop symptoms of rhinovirus, whereas if those who slept more than 7 hours for a week, only 18% developed rhinovirus after it was sprayed up their nose.
- One night of 4 hours of sleep leads to a 70% drop in natural killer cells—the ones that detect and destroy cancer.
- Night shift work has been labeled a probable carcinogen by the World Health Organization.
- Studies link chronic sleep deprivation with breast, prostate, colon, and endometrial cancers.
- Sleep-deprived mice show 200% faster tumour growth and more aggressive spread.
- Inflammation ramps up, immune surveillance goes offline, and tumours exploit the chaos.
And then there’s this:
Sleep-deprived flu shots produce 50% fewer antibodies.
No sleep = no immunity.
Sleep isn’t a luxury.
It’s an immune therapy, a hormonal rebalancer, a fat-burning furnace, and a fertility enhancer.
Sleep and the Emotional Brain: When Compassion Goes Offline
Let’s talk about behaviour.
Not data. Not hormones.
But how you show up in the world when you’re underslept.
It’s not good.
- You snap at colleagues.
- You misread intent.
- You get in pointless arguments.
- You write angry emails you regret.
- You lose patience with your kids—and with yourself.
You stop being the person you trained to be.
The Science Behind It
MRI studies show that sleep deprivation increases reactivity in the amygdala by up to 60%.
That’s the threat detector of your brain—fight, flight, or freak out.
But what normally keeps it in check?
The prefrontal cortex—your logic, empathy, and restraint centre.
When you’re underslept, the connection between these two regions fractures.
Result? Your amygdala runs hot, your brakes are off, and the filter is gone.
You become more impulsive. More reactive. More emotionally volatile.
You start perceiving neutral expressions as threatening, constructive feedback as criticism, and minor stressors as catastrophic.
REM Sleep: The Overnight Therapist
Here’s where it gets fascinating:
- REM sleep strips the emotional charge from painful memories.
- It allows you to revisit stress without reliving the trauma.
- During REM, the brain suppresses norepinephrine, the fight-or-flight hormone.
Without REM?
- Emotional memories stay raw, unprocessed, wound-like.
- You ruminate.
- You overreact.
- You lose emotional intelligence.
In studies, people deprived of REM sleep:
- Struggled to read facial expressions
- Had impaired micro-emotion detection
- Were more likely to perceive faces as hostile
In medicine, where decisions, trust, and compassion matter?
That’s dangerous.
Chronic Sleep Loss → Chronic Conflict
Underslept people are:
- Less empathic
- More irritable
- Worse at resolving conflict
- Perceived by others as colder, more self-focused, and less cooperative
Your personality doesn’t change—your access to it does.
You’re still kind. Still patient. Still rational.
But sleep deprivation cuts the cable between who you are and how you behave.
So if you’ve ever:
- Hit “send” on a regrettable email
- Snapped at a junior doctor
- Argued with a partner over nothing
- Or felt numb to a patient’s pain…
Ask yourself:
Are you a bad person—or just a tired one?
Sleep restores your compassion bandwidth.
Sleep makes you a better doctor, colleague, parent, and partner.
Sleep and the Psychiatric Fallout: When the Mind Unravels
There is no psychiatric disorder where sleep is normal.
None.
From depression to anxiety, bipolar disorder to PTSD—disrupted sleep is the rule, not the exception.
But here’s what’s often missed:
Sleep disruption doesn’t just follow mental illness.
It causes, worsens, and mimics it.
Sleep Deprivation Looks Like Mental Illness
In experimental studies, when healthy individuals are deprived of sleep:
- They develop mood swings
- Show increased anxiety and irritability
- Display risk-taking behaviour
- Experience paranoia, hallucinations, and memory distortion
In short: you can induce psychiatric symptoms by simply keeping someone awake.
It’s a two-way street:
Mental illness affects sleep.
Poor sleep mimics or amplifies mental illness.
REM Sleep and Emotional Recovery
- REM sleep fine-tunes our ability to recognize emotional cues, like facial expressions and tone.
- It suppresses overactive limbic circuits (like the amygdala), allowing us to see the world more clearly.
- PTSD patients often have REM sleep disruptions, leading to emotional overdrive and vivid nightmares.
In healthy sleep, norepinephrine levels drop during REM—this allows you to revisit trauma without reliving the fear.
But if you’re sleep deprived?
- Norepinephrine remains high.
- Emotional memory stays raw.
- Your brain keeps looping the fear circuit, night after night.
This may explain why chronic nightmares are a hallmark of PTSD—and why restoring REM sleep (or pharmacologically suppressing norepinephrine, e.g. with prazosin) can be therapeutic.
Sleep and Alzheimer’s: The Toxic Build-Up
Here’s the part that should terrify every high-functioning insomniac:
Sleep deprivation increases your risk of Alzheimer’s disease.
Here’s how it works:
- During deep NREM sleep, your brain activates the glymphatic system—a waste clearance pathway that flushes out amyloid-beta and tau proteins, the key culprits in Alzheimer’s pathology.
- The most effective clearance occurs during slow-wave (Stage 3 NREM).
Without sleep, this clean-up crew doesn’t run.
And the trash piles up.
Imaging studies show:
- Just one night of sleep deprivation causes measurable amyloid accumulation in the medial prefrontal cortex—the very region responsible for generating deep sleep.
- This creates a vicious cycle:
- Less sleep → more amyloid → less ability to sleep deeply → more amyloid.
That’s how insomnia can become a self-fulfilling prophecy of cognitive decline.
Why Can’t We Sleep?
Because we’ve broken the two biological gears that power the sleep-wake cycle:
1. Circadian Rhythm: The Master Clock
Your circadian rhythm is your internal 24-hour timekeeper—a finely tuned biological metronome that governs when you feel alert and when you feel sleepy.
It’s driven by a cluster of ~20,000 neurons in your suprachiasmatic nucleus (SCN), located in the hypothalamus.
Think of it as your body’s conductor, orchestrating a hormonal symphony:
- Morning sunlight hits your retina → sends signals to the SCN → suppresses melatonin, boosts cortisol and alertness.
- Darkness triggers pineal gland release of melatonin, signalling your body it’s time to sleep.
It controls:
- Body temperature
- Blood pressure
- Hormone release
- Digestion
- Mental performance
- Mood
But it has one major limitation:
Your circadian rhythm naturally drifts slightly longer than 24 hours (24 hours and 15 minutes).
It needs daily light cues to reset.
Disrupt that light/dark input, and the whole system goes out of tune.
Enter:
- Late-night screen time
- Artificial light
- Night shifts
- Jet lag
- Inconsistent sleep/wake times
You’re now running on biological jet lag—even if you never leave your time zone.
And here’s the kicker:
Your circadian clock can only adjust by ~1 hour per day.
So if you shift your schedule by 3–4 hours (say, weekend warrior or night shift)?
You’re several days behind, biologically speaking.
2. Sleep Pressure: The Internal Hourglass
While circadian rhythm tells you when to sleep, sleep pressure tells you how badly you need to.
It’s regulated by adenosine—a neurochemical that builds up in your brain the longer you’re awake.
- Wake = adenosine builds
- Sleep = adenosine clears
- The longer you’re up, the stronger the pressure to crash
Caffeine doesn’t reduce adenosine—it just blocks the receptors, like putting noise-cancelling headphones on with a screaming child in the room.
Eventually, the pressure breaks through. That’s the “caffeine crash.”
Here’s the catch:
Adenosine clearance isn’t instant.
You can’t “nap it off.”
You need 7–9 hours of sleep—and especially deep NREM—to reset it fully.
So if you cut your sleep short or fragment it?
- You wake up with residual adenosine,
- You feel groggy (aka “sleep inertia”),
- You reach for caffeine…
- …and the cycle begins again.
Sleep pressure is like metabolic gravity:
You can’t beat it. You can only respect it.
When These Rhythms Clash
Here’s the kicker:
- Circadian Rhythm says: “It’s 11 PM. Let’s wind down.”
- Sleep Pressure says: “Sorry, we slammed 3 espressos at 4 PM and just binge-watched a dopamine firehose on Netflix.”
When these systems are out of sync, you feel tired but wired.
Or worse—you can’t fall asleep at all.
Optimal sleep happens when:
Circadian rhythm is aligned with the natural light/dark cycle, and
Sleep pressure has built up over 16 hours of clean wakefulness (no naps, no caffeine cheats)
The Pareto Principle for Peak Performance
Enter the 80/20 rule—The Pareto Principle.
80% of your outcomes come from 20% of your actions.
You don’t need 100 sleep hacks. You need the vital few that unlock the high-performance many.
That’s how we’ll break this down.
What’s Next?
In Part 2, we hit the 80/20 of elite sleep:
The high-yield, no-nonsense tactics that reclaim your edge—without quitting your job, moving to Bali, or buying a weighted blanket made from moon rocks.
In Part 3, we focus on sleeping like a shift worker: The 80/20 Guide to Owning the Night. Not everyone gets to sleep from 10 PM to 6 AM wrapped in a $300 bamboo blanket listening to Tibetan wind chimes.
I can’t wait for the next posts. Why not self-experiment, try getting 8 hours of sleep, and do you feel good? Why not try doing that for 6 weeks in a row and see how you feel?
Because when you out-sleep the competition…
You outthink, outheal, outcreate, and outlast them.
Reference:
The sole academic reference to these sleep posts comes from Dr Matthew Walker from his book Why We Sleep. If you have the time, it’s a must read, and he doesn’t mind if it puts you to sleep!
- Dr Matthew Walker: Why We sleep – unlocking the power of sleep and dreams. 2018
- The Matt Walker podcast
Sleep Series:
- Out-Sleep the Competition: Part 1. Sleep as a Peak Performance State
- Out-Sleep the Competition: Part 2. The 80/20 of Elite Sleep
- Out-Sleep the Competition: Part 3. The 80/20 Guide to Owning the Night
Dr Neil Long BMBS FACEM FRCEM FRCPC. Emergency Physician at Kelowna hospital, British Columbia. Loves the misery of alpine climbing and working in austere environments (namely tertiary trauma centres). Supporter of FOAMed, lifelong education and trying to find that elusive peak performance.