The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Reviewed and revised 31 December 2015 OVERVIEW Obesity is the chronic abnormal or excessive accumulation of fat in adipose tissue to the extent that health may be impaired degrees of obesity are defined by body mass index (BMI) OBESITY PARADOX…
Drug withdrawal in ICU is more common than generally appreciated.
Haemoperfusion: Renal replacement therapy (RRT) using an adsorbent cartridge to remove circulating toxins
Extracorporeal Elimination recommended for the following intoxications: methotrexate, procanamide, lithium, metformin, ethanol, methanol, ethylene glycol, salicylates, theophylline, sodium valproate.
The role for digestive tract decontamination depends on: severity of poisoning; time from ingestion; risk of intervention
Monoamine Oxidase Inhibitor (MAOI) Toxicity produces a hyperadrenergic syndrome from inability to inactivate noradrenaline; may contribute to serotonin toxidrome
Retrospective studies are designed to analyse pre-existing data, and are subject to numerous biases as a result. Types of retrospective studies include: case series; retrospective cohort studies; case-control studies
Leukotriene Receptor Antagonists example is Montelukast
Pleural Effusion secondary to blood; exudate; transudate; and chyle
Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are novel coronaviruses that cause severe viral pneumonia in humans
Most coronavirus infections are mild respiratory tract infections
Surgical Emphysema
Wheeze indicates lower airway obstruction, which can be due to the following factors: luminal; intramural; extramural