Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care compendium 340

Fluid Responsiveness

Fluid responsiveness is an increase of stroke volume of 10-15% after the patient receives 500 ml of crystalloid over 10-15 minutes (as defined by Paul Marik). The definitive test for fluid responsiveness is a Fluid challenge

CCC Critical Care compendium 340

Obesity and Pharmacokinetics

Obesity affects all four aspects of pharmacokinetics. As drug administration based on total body weight can result in in underdosing or overdosing, depending on the characteristics of the drug, weight-based dosing scalars must be considered. Lean body weight is the optimal scalar for most IV opioids and anaesthetics

CCC Critical Care compendium 340

Obesity and Critical Illness

Reviewed and revised 31 December 2015 OVERVIEW Obesity is the chronic abnormal or excessive accumulation of fat in adipose tissue to the extent that health may be impaired degrees of obesity are defined by body mass index (BMI) OBESITY PARADOX…

CCC Critical Care compendium 340

Haemoperfusion

Haemoperfusion: Renal replacement therapy (RRT) using an adsorbent cartridge to remove circulating toxins

CCC Critical Care compendium 340

Extracorporeal Elimination in Toxicology

Extracorporeal Elimination recommended for the following intoxications: methotrexate, procanamide, lithium, metformin, ethanol, methanol, ethylene glycol, salicylates, theophylline, sodium valproate.

CCC Critical Care compendium 340

Retrospective Studies and Chart Reviews

Retrospective studies are designed to analyse pre-existing data, and are subject to numerous biases as a result. Types of retrospective studies include: case series; retrospective cohort studies; case-control studies