= immune complex mediated hypersensitivity -> severe erythema multiforme. Separation of the epidermis from the dermis; most authors believe toxic epidermal necrolysis (TEN) and SJS are different ends of the same spectrum of disease
Is it safe to give a patient frusemide if he has an allergy to sulfa drugs? Are you feeling slightly immunologically discombobulated? The answer's here.
Alan Lyell (1917-2007) was a Scottish Dermatologist. Lyell Syndrome (1956) AKA toxic epidermal necrolysis.