When it first came out, crotalidae polyvalent immune Fab (CroFab), was seen as a godsend by many. It didn’t cause anaphylaxis or serum sickness to nearly the same degree as the old product.
Antivenom is widely used for Australian envenoming syndromes. Antivenoms are generally perceived, by both clinicians and the general public, as highly effective treatments. However, there is little evidence to support this widely held view, in fact, the weight of evidence suggests that some antivenoms are ineffective in clinical practice.