Lithium toxicity
Lithium is commonly used to treat bipolar, for your toxicology encounter it will come in two varieties, either an acute overdose or chronic toxicity and it is important to distinguish the two (examiners love this question).
Lithium is commonly used to treat bipolar, for your toxicology encounter it will come in two varieties, either an acute overdose or chronic toxicity and it is important to distinguish the two (examiners love this question).
Your next patient has swallowed over 80 grams of lithium. What are you going to do about it?
Lithium: mood stabiliser; element of the alkali metal group; exact mechanism of action in mania is unknown
Lithium: acute overdose is usually benign if adequate hydration is maintained and renal function is normal; chronic toxicity can be difficult to manage and result in devastating neurotoxicity
The case. 64 year old female who is day 1 post elective left total-knee replacement. She has a past medical history of osteoarthritis, bipolar disorder and depression for which she takes quetiapine, lithium and paracetamol. You are asked to see her on…