Michael Antony Denborough (1929 – 2014) was an Australian anaesthetist, academic, activist and medical researcher. First described malignant hyperthermia (Maladie de Denborough)
Toxidrome challenge lets you test yourself on anticholinergic toxicity, malignant hyperthermia, neuroleptic malignant syndrome, and serotonin syndrome.
Malignant Hyperthermia = pharmacogenetic disease of skeletal muscle induced by exposure to certain anaesthetic agents; incidence 1:5,000 -> 1:65,000 anaesthetics (suspected); mutation in the gene coding for the ryanodine receptor
Toxidromes associated with hyperthermia may be difficult to distinguish: serotonin syndrome; anticholingeric syndrome; sympathomimetic syndrome; neuroleptic malignant syndrome; malignant hyperthermia