Tag Monro-Kellie doctrine
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Alexander Monro secundus

Alexander Monro secundus (1733-1817) was a Scottish physician and anatomist. Most notable contributions include works on the lymphatic system, the interventricular foramen (of Monro), and the Monro-Kellie doctrine
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Monro-Kellie doctrine

The Monro-Kellie doctrine or hypothesis states that the sum of volumes of brain, cerebrospinal fluid (CSF) and intracerebral blood is constant. An increase in one should cause a reciprocal decrease in either one or both of the remaining two.