Network Five: Toxicology
In this exciting episode, we will be discussing the role of DigiFab in chronic digoxin toxicity before diving into an interesting case of organophosphate poisoning
Tag Organophosphate poisoning
Organophosphate Poisoning
Organophosphate Poisoning: common cause of poisoning in the developing world; covalent bonding with inactivation of acetylcholinesterase; results in cholinergic crisis
Atropine
Atropine is a competitive muscarinic antagonist, used to treat drug-induced bradycardia and poisoning by acetylcholinesterase inhibitors Organophosphate poisoning: Adult Dose = 1.2mg with further dosing every 2-3 mins, doubling the dose each time until there is drying of secretions. Paediatric…