Tag Organophosphate poisoning
CCC Critical Care compendium 340

Organophosphate Poisoning

Organophosphate Poisoning: common cause of poisoning in the developing world; covalent bonding with inactivation of acetylcholinesterase; results in cholinergic crisis

Atropine

Atropine is a competitive muscarinic antagonist, used to treat drug-induced bradycardia and poisoning by acetylcholinesterase inhibitors Organophosphate poisoning: Adult Dose = 1.2mg with further dosing every 2-3 mins, doubling the dose each time until there is drying of secretions. Paediatric…