Tag Organophosphate poisoning
Network Five Journal Club Podcast 340

Network Five: Toxicology

In this exciting episode, we will be discussing the role of DigiFab in chronic digoxin toxicity before diving into an interesting case of organophosphate poisoning
CCC Critical Care compendium 340

Organophosphate Poisoning

Organophosphate Poisoning: common cause of poisoning in the developing world; covalent bonding with inactivation of acetylcholinesterase; results in cholinergic crisis


Atropine is a competitive muscarinic antagonist, used to treat drug-induced bradycardia and poisoning by acetylcholinesterase inhibitors Organophosphate poisoning: Adult Dose = 1.2mg with further dosing every 2-3 mins, doubling the dose each time until there is drying of secretions. Paediatric…