Pharm 101: Phenytoin
ACEM Primary Pharmacology of Phenytoin: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects
ACEM Primary Pharmacology of Phenytoin: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects
Phenytoin intoxication can occur either with repeated supra therapeutic dosing or an acute overdose. Dose-dependent CNS depression occurs. Most presentations are benign and have good outcomes with supportive care. The main risk to patients is falling which can last days.