Levetiracetam (keppra) is a drug used as an anticonvulsant as monotherapy, or an adjunct, and as a Tier 2 agent in status epilepticus.
Network Five Emergency Medicine Journal Club Episode 16 - Neurology reviewing papers from vertigo, GBS to status epilepticus.
Thiopentone is a hypnotic and anticonvulsant medication. It is used in anaesthesia, treatment of status epilepticus and neuroprotection.
A 22 year old female is BIBA in status epilepticus. She is believed to have overdosed on her discharge medications following a month long stay as an inpatient on the psychiatric ward.
Status epilepticus is considered to have occurred when a generalised tonic-clonic seizure has lasted greater than 30 minutes.
Status epilepticus: continuous seizure activity for 5 minutes or more without return of consciousness, or recurrent seizures (2 or more) without an intervening period of neurological recovery
Non-Convulsive Status Epilepticus (NCSE) is a persistent change in the level of consciousness, behaviour, autonomic function, and sensorium from baseline associated with continuous epileptiform EEG changes, but without major motor signs
Seizures are the manifestation of abnormal hyperexcitable discharges of cortical neurons. 10 minutes of continuous seizure activity is now considered status epilepticus, which may result in neuronal damage. Seizures should be aggressively treated if they last longer than 5 minutes.