Takayasu arteritis


Takayasu M. 第十三席 高安君 奇異ナル網膜中心血管ノ變化ノ一例 [A Peculiar Case of Changes in the Retinal Central Vessels]. Nihon Ganka Gakkai Zasshi (Acta Societatis Ophthalmologicae Japonicae). 1908; 12: 554-555.

Japanese (Verbatim)English Translation
第十三席 高安君 奇異ナル網膜中心血管ノ變化ノ一例13th Presentation – Mr. Takayasu: A Peculiar Case of Changes in the Retinal Central Vessels
三十八年五月一婦人ニテ奇ナナル一例ヲ見タリ。In May of this year, I observed a remarkable case in a woman.
既往症トシテ昨年九月初旬ヨリ視界濛々タリキ。According to her history, since early September of last year her visual field had appeared clouded and indistinct.
同時ニ結膜充血アリ。醫療ヲ受ケズ。是迄ノ病氣ハナシ。At the same time, there was conjunctival hyperemia. She had not received medical treatment and had no prior illnesses.
瞳孔反應アリ。視力少シク遲鈍ナリ。内科的變化ナシ。Pupillary reactions were present but slightly sluggish. No systemic abnormalities were detected.
眼底ヲ檢スルニ、乳頭ヲ圍繞セル血管環アリ。花環狀ヲ呈シ、血管相互二交通吻合ヲナシ、乳頭周圍ヲ環狀ニ繞リテ存ス。On ophthalmoscopic examination, a vascular ring was seen encircling the optic disc. The vessels formed a garland-like arrangement, with numerous anastomoses, completely surrounding the papilla in a circular pattern.
又其外方ニ於テモ同樣ノ異常ノ血管走行ヲ見ル。Additional vascular loops of similar abnormal character were observed beyond this, toward the periphery.
其後、瞳孔散大シ、眼球少シク陷沒シ、血管變化ハ依然トシテ存ス。Later, the pupil dilated, the globe became slightly sunken, yet the vascular anomaly persisted unchanged.
ピロカルピンノルピン發汗注射、食鹽水注射、臭素加里共二試ミシモ効ナク、視力次第二減退シ、指數辨ズルニ至リ、白內障ヲ發シ、手術ヲ試ムルモ効ナク、遂ニ失明ニ至レリ。Various therapies were attempted, including pilocarpine, diaphoresis injections, saline injections, and potassium bromide, but without effect. Vision gradually declined until only finger counting was possible. Cataract developed; surgical treatment was attempted without success, and finally blindness ensued.
本症ノ變化ハ、花環狀血管ノ繞リテ乳頭ヲ包圍セルモノニシテ、實ニ稀有ナル所見ナリ。The vascular change consists of garland-like vessels encircling the optic disc—a truly rare and extraordinary finding.

Discussion points:

JapaneseEnglish
阿部君: 本患者ハ、兩側ノ橈骨動脈ニ脈搏ヲ觸レズ。然レドモ前膊冷ナラズ。甚ダ奇異ナリ。Dr. Abe: In this patient, the radial pulses in both arms could not be palpated, though the forearms were not cold. This is extremely unusual.
大西君: 予ノ教室ニ於テモ同樣ノ患者アリ。環狀吻合ヲナセル血管環及ビ其ガ動脈瘤樣ノモノヲ有スルコト、高安君ノ述ベル所ト酷似セリ。Dr. Ōnishi: In my department, a similar patient is under observation. Around the optic disc, there is a vascular ring with multiple anastomoses, some aneurysmal in appearance—closely resembling the condition described by Mr. Takayasu.

Physician in training. German translator and lover of medical history.

BA MA (Oxon) MBChB (Edin) FACEM FFSEM. Emergency physician, Sir Charles Gairdner Hospital. Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books |

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