sigmoid shape of the oxy-Hb dissociation curve results from the allosteric interactions of the globin monomers that make up the haemoglobin tetramer as each one binds O2. Multiple factors can affect the affinity of Hb for oxygen, thus causing the curve to shift to the left (increased oxygen affinity) or to the right (decreased O2 affinity)
Acute Respiratory Distress Syndrome (ARDS) Literature Summaries
Flow versus Time Graph: constant flow = volume control; decelerating flow = any mode
Clinical Cases Hyperkalaemia DDx Hyperkalaemia management Hyperkalemia Case Study Causes of HYPERkalaemia Serum potassium levels above the normal range (3.5-5.0 mmol/L) 1) Increased potassium intake (rare) Oral (potassium supplements) IV (transfusion of stored blood, supplement infusions) 2) Increased production Tissue…
Recurrent facial twitches are most commonly due to hemifacial spasm, but this needs to be distinguished from other causes.
Parkinsonism is a combination of resting tremor, rigidity, bradykinesia, and loss of postural reflexes. Parkinson disease (PD) is the most common form, but must be distinguished from its imitators.
Daily fluid balance is the daily sum of all intakes and outputs, and the cumulative fluid balance is the sum total of fluid accumulation over a set period of time. The harmful effects of positive fluid balance and the importance of deresuscitation
Pierre Eugène Ménétrier (1859 – 1935) was a French surgeon, oncologist and pathologist. Eponymously affiliated with Maladie de Ménétrier (1888)
Abdominal distension is diffuse swelling or enlargement of the abdomen. It can also apply to the sensation of elevated abdominal pressure and volume.
Acanthosis nigricans are black brown velvety elevations of the epidermis. Differential diagnosis
Alcohol Withdrawal: common and can be fatal; manifests within 48 hours of stopping drinking
Coming to terms with depression and mental health issues in the world of medicine