Month January 2019
CCC Critical Care compendium 340

Fluid Challenge

The fluid challenge (FC) aims at identifying patients in whom fluid administration improves haemodynamics (known as "fluid responsiveness")

CCC Critical Care compendium 340

Adaptive Trial Designs

An adaptive clinical trial involves a study design in which key characteristics are adjusted while enrollment in the trial is ongoing using prospectively defined decision rules and in response to information arising from the data accumulating in the trial

CCC Critical Care compendium 340

Chi-square Test

Chi-square Test is used to compare categorical data; often displayed in contingency table with rows (x) and columns (y)

CCC Critical Care compendium 340

Clenbuterol toxicity

Reviewed and revised 24 May 2014 OVERVIEW MECHANISM OF ACTION TOXICOKINETICS RISK ASSESSMENT CLINICAL FEATURES Effects include: Complications INVESTIGATIONS (Guided by clinical assessment) Laboratory tests MANAGEMENT Resuscitation Supportive care and monitoring Decontamination Disposition References and Links Journal articles

CCC Critical Care compendium 340

Enhanced Elimination

Enhanced elimination techniques serve to increase the rate of removal of an agent from the body with the aim of reducing the severity and duration of clinical intoxication.

CCC Critical Care compendium 340

High-dose Insulin Euglycaemic Therapy

High-dose Insulin Euglycaemic Therapy (HIET) is primarily used in the therapy of severe calcium channel blocker toxicity. HIET can also be used for severe beta blocker toxicity and potentially other toxicities/ presentations requiring inotropic support

CICM Exam Library 340

CICM SAQ 2015.2 Q28

A 76-year-old female is admitted to the ICU following elective aortic and mitral valve replacement. Trans- oesophageal echo assessment at the end of surgery showed an ejection fraction of 20%. Her preoperative creatinine was 340 μmol/L. Total bypass time was 240 minutes.