FEAST and Paediatric Fluid Resuscitation
FEAST = Fluid Expansion As Supportive Therapy. Trial was a landmark study investigating the effects of fluid boluses in the resuscitation of febrile children with evidence of poor perfusion
Month January 2019
Pharmacology and Critical Illness
In simple terms, pharmacodynamics is "how the drug effects the body" and pharmacokinetics is "how the body handles the drug"; changes also occur in obesity, pregnancy, old age and the very young which may each coexist with critical illness
Surviving Sepsis Campaign Guidelines 2008
These guidelines (and this webpage) has been superseded by the Surviving Sepsis Campaign Guidelines 2012
Steroids and Septic Shock Literature Summaries
Bone R.C. et al (1987) “A controlled clinical trial of high dose methylprednisolone in the treatment of severe sepsis and septic shock” NEJM, 317:653-658 PMID 3306374 RCT n = 382 with sepsis and organ dysfunction methylprednisolone (30mg/kg) vs placebo-> no…
Septic emboli
Septic embolism involves two insults: the early embolic/ischaemic insult due to vascular occlusion; and the infectious insult from a deep-seated nidus of infection
RAPTOR suite
The RAPTOR suite is hybrid unit designed for both interventional radiology and operative interventions. RAPTOR is acronym for 'Resuscitation with angiography, percutaneous techniques and operative repair'
Trauma Mortality and the Golden Hour
The ‘golden hour’ is term often used in trauma to suggest that an injured patient has 60 minutes from time of injury to receive definitive care, after which morbidity and mortality significantly increase
Cholecystitis
cholecystitis = inflammation of the gall bladder; causes: mechanical, chemical and infectious -> mucosal injury; complications: pancreatitis, ascending cholangitis, gall bladder empyema, gangrene
Lightning injury
Potentially lethal electrical injury due to lightning exposure; 24,000 deaths/ year worldwide
Smoke inhalation
Smoke is a complicated heterogeneous mixture of potentially toxic gases, chemical fumes, asphyxiants and particulate debris. Smoke inhalation is commonly seen in patients with burns as a result of fire; it is associated with high morbidity and mortality
Prevention of Electrocution
Prevention of electrocution in the hospital setting
Central Diabetes Insipidus
Diabetes insipidus (DI) is a condition caused by loss of the effect of antidiuretic hormone on the collecting ducts of the kidneys, resulting in loss of free water.