Sylvester McGinn

Sylvester McGinn (1904-1984) was an American cardiologist
Along with colleague Paul White (1886-1973), he first described the so-called S1Q3T3 pattern in five patients with acute cor pulmonale secondary to pulmonary embolism.
Biography
- Born on December 26, 1904
- 1926 – BA, Dartmouth
- 1929 – MD, Harvard medical school
- 1932 – Dalton Fellow, Cardiac clinics and Laboratory Massachusetts General Hospital
- 1938 – Instructor in Medicine, Harvard Medical School
- 1941 – Cardiologist, Robert Breck Bingham Hospital
- 1943 – Lt Commander in the United States Navy
- 1946 – Consultant in cardiology at the Waltham Hospital
- 1951 – Director of the Massachusetts Heart Association
- 1955 – Chief of medicine and cardiologists at St. Elizabeth’s Hospital; President of the Greater Boston Chapter of the State Heart Association; and on the National Council of Clinical Cardiology
- Died January 13, 1984 at Manatee County, Florida
Medical Eponyms
McGinn-White pattern (1935)
SI QIII TIII pattern on ECG representing right heart strain in an acute pulmonary embolism. McGinn and White first described the so-called S1Q3T3 pattern in five patients with acute cor pulmonale secondary to pulmonary embolism.
(1)The prominent S wave and low origin of the T wave in lead 1, the ST segment starting slightly below the baseline, (2) the gradual staircase ascent of the ST interval from the S wave to the T wave in lead 2, and especially (3) the Q wave and definite late inversion of the T wave in lead 3.
McGinn S and White PD
Major Publications
- McGinn S, White PD. A Follow-up Report on the Clinical Study of Two Hundred and Fifty Cases of Cardiac Asthma and a Survey of an Additional Group of Twenty-Two New Cases. N Engl J Med 1932; 207: 1069-1073
- McGinn S, White PD. Clinical Observations on Aortic Stenosis. Trans Am Clin Climatol Assoc. 1933; 49: 132-44
- McGinn S. Progress in the Study of Cardiovascular Disease in 1934. N Engl J Med 1935; 213: 1293-1303
- McGinn S, White PD. Acute cor pulmonale resulting from pulmonary embolism. JAMA. 1935; 104(17): 1473-1480 [McGinn-White pattern; defined acute cor pulmonale]
- Sprague HB, McGinn S. A Series of Cases in Which the Electrocardiographic Lead from the Cardiac Apex Was the Chief Diagnostic Aid in Coronary Occlusion. Trans Am Clin Climatol Assoc. 1937; 53: 81-91.
- Sprague HB, McGinn S. The Apical Chest Lead as the Chief Aid in the Diagnosis of Coronary Occlusion. N Engl J Med 1938; 218: 555-560
- McGinn S, Spear LM. Diaphragmatic Hernia Presenting the Clinical Picture of Acute Cor Pulmonale – Report of a Case. N Engl J Med 1941; 224: 1014-1018
- Sprague HB, McGinn S. Heart diseases and disorders as causes for evacuation from the South Pacific combat area. American Heart Journal, 1944; 27(4): 568–574
References
Biography
- Photo: Sylvester McGinn. Dartmouth Alumni 1956: 59
- Class of 1926. Dartmouth Alumni 1957
- Obit: Sylvester McGinn. In: Massachusetts Medical Society. New England Journal of Medicine, 1984; 310(12): 787
- Bibliography. McGinn, Sylvester. WorldCat Identities
Eponymous terms
- Karn M, Yonghang S, Barma A, Sharma A. The classic S1Q3T3/McGinn-White sign in acute pulmonary embolism. QJM. 2024 Sep 1;117(9):665-666
- Teng F, Chen YX, He XH, Guo SB. Contribution of Quick Sequential Organ Failure Assessment Score Combined with Electrocardiography in Risk Stratification of Patients with Acute Pulmonary Embolism. Chin Med J (Engl). 2018 Oct 20;131(20):2395-2401.
- Golzarian H, Chakraborty S, Shaikh MU, Hinegardner-Hendricks J, Toro DF. Severe Acute Cor Pulmonale With Impending Shock: An Insidious Incidental. JACC Case Rep. 2024 Feb 9;29(6):102241
Eponym
the person behind the name