High Volume Haemofiltration
High volume haemofiltration (HVH) is CRRT where the filtration rate is large - aka “high-volume,” “high intensity,” or “high flow”
Category CCC
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Initial Management of Sepsis
Reviewed and revised 17 September 2019 OVERVIEW Initial management of sepsis and septic shock involves consideration of: resuscitation early administration of appropriate antibiotics following blood cultures early source control judicious fluid resuscitation, avoiding excess fluids noradrenaline for refractory hypotension (septic shock) inotropes…
Fatigue and the Critical Care Doctor
Fatigue = sleep and rest deprivation that negatively impacts on performance
Open Disclosure
Open Disclosure is the process of communicating with a patient and/or their support person(s) about a patient-related incident or harm caused during the process of healthcare
Activated Protein C
Activated Protein C: endogenous human protein; recombinant glycoprotein with anti-thrombotic, profibrinolytic and anti-inflammatory properties.
Cessation of CPR
The decision to stop CPR should be tailored according to the specifics of the individual case and is based on clinical judgement. The decision is best made by the Team Leader in consultation with other team members
Intra-arrest therapeutic hypothermia
Therapeutic hypothermia (T33°C) after return of spontaneous circulation (ROSC) was not found to confer benefit compared to normothermia (T36°C) in the TTM trial
Passive Leg Raise
Passive Leg Raise (PLR) transiently increases venous return in patients who are preload responsive, as such it is a diagnostic test not a treatment. It is a predictor of Fluid responsiveness
Summary of RRT Types
References and Links CCC – RRT Indications CCC – RRT principles in fluid management CCC – RRT Types CCC – RRT terminology and nomenclature CCC – RRT troubleshooting CCC – Renal Literature Summaries DerangedPhysiology.com CVVH: Continous Veno-Venous Hemofiltration circuit diagram…
Renal replacement therapy: Terminology
Renal Replacement Therapy (RRT) Terminology and Nomenclature
Gastric lavage
Gastric lavage is a GI decontamination technique that aims to empty the stomach of toxic substances by the sequential administration and aspiration of small volumes of fluid via an orogastric tube. Previously widely favoured method that has now been all but abandoned due to lack of evidence of efficacy and risk of complications.
Organophosphate Poisoning
Organophosphate Poisoning: common cause of poisoning in the developing world; covalent bonding with inactivation of acetylcholinesterase; results in cholinergic crisis