
Fatigue and the Critical Care Doctor
Fatigue = sleep and rest deprivation that negatively impacts on performance
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

Fatigue = sleep and rest deprivation that negatively impacts on performance

Open Disclosure is the process of communicating with a patient and/or their support person(s) about a patient-related incident or harm caused during the process of healthcare

Activated Protein C: endogenous human protein; recombinant glycoprotein with anti-thrombotic, profibrinolytic and anti-inflammatory properties.

The decision to stop CPR should be tailored according to the specifics of the individual case and is based on clinical judgement. The decision is best made by the Team Leader in consultation with other team members

Therapeutic hypothermia (T33°C) after return of spontaneous circulation (ROSC) was not found to confer benefit compared to normothermia (T36°C) in the TTM trial

Passive Leg Raise (PLR) transiently increases venous return in patients who are preload responsive, as such it is a diagnostic test not a treatment. It is a predictor of Fluid responsiveness

References and Links CCC – RRT Indications CCC – RRT principles in fluid management CCC – RRT Types CCC – RRT terminology and nomenclature CCC – RRT troubleshooting CCC – Renal Literature Summaries DerangedPhysiology.com CVVH: Continous Veno-Venous Hemofiltration circuit diagram…

Renal Replacement Therapy (RRT) Terminology and Nomenclature

Gastric lavage is a GI decontamination technique that aims to empty the stomach of toxic substances by the sequential administration and aspiration of small volumes of fluid via an orogastric tube. Previously widely favoured method that has now been all but abandoned due to lack of evidence of efficacy and risk of complications.

Organophosphate Poisoning: common cause of poisoning in the developing world; covalent bonding with inactivation of acetylcholinesterase; results in cholinergic crisis

the radioactive isotope polonium-210 was implicated in the death of former KGB/ FSB operative Alexander Litvenko;
also has potential for use in nuclear terrorism as a 'dirty bomb'

Transfusion Literature Summaries