Logistic regression analysis
Logistic regression analysis is used to predict a dependent binary outcome (yes/no, dead/alive) based on one or more predictor variables
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Logistic regression analysis is used to predict a dependent binary outcome (yes/no, dead/alive) based on one or more predictor variables
Cervical Spine Fractures
Burns are injuries to tissues caused by heat, friction, electricity, radiation, or chemicals. Burn injury is characterised by a hypermetabolic response with physiologic, catabolic and immune effects
Glucagon is traditionally considered a first line antidote for beta-blocker overdose. Glucagon has also been used in the setting of calcium channel blocker toxicity
Digibind: trade name for digoxin antidote containing Digoxin-specific antibody Fab fragments; prudent to administer based on a considered risk assessment and before the life-threatening manifestations of digoxin toxicity develop
Digoxin toxicity is characterised by gastrointestinal distress, hyperkalemia and life-threatening dysryhthmias, including increased automaticity and AV nodal blockade
Activated Charcoal: decontamination agent; absorbing molecules of drug on its surface -> inhibiting their absorption by as much as 50% -> excretion in faeces
Renal Literature Summaries
Optimal dose of renal replacement therapy (RRT) is controversial... the definition of dose in clinical practice is also a little controversial!
Continuous Renal Replacement Therapy (CRRT) Circuits: used in renal replacement therapy; therapeutic plasma exchange; and haemoperfusion
Sepsis Literature Summaries
Opioid Withdrawal