The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Haemoptysis is the symptom of coughing up blood. Massive haemoptysis has no generally accepted definition. Suggested volumes range from 100 mL to more than 1000 mL. A more relevant definition of massive haemoptysis is the volume that is life threatening by virtue of airway obstruction or blood loss (anatomical dead space is only 100-200 mL)
Honeycomb lung differential diagnosis
Increased interstitial markings seen on chest x-ray may also be referred to as a fine reticular pattern
Abnormal vital signs in patient's following toxic exposures can suggest underlying toxidromes. Differential diagnosis of abnormal signs
Causes of pulmonary fibrosis can be divided into those that affect the upper lobes and those predominantly affecting the lower lobes
The differential diagnosis of toxicological causes of cardiac arrest are many and varied. It is useful to consider the causes in terms of mechanism.
OVERVIEW CLINICAL FEATURES INVESTIGATIONS MANAGEMENT -> ethanol dose (IV): 10% solution in D5W as a 40% solution, loading dose 7.5mL/kg -> 1-2mL/kg/hr-> ethanol dose (PO): quarter the above dose-> dose in CRRT: double IV dose-> maintain ethanol level @ 25-40mmol/L…
The Randomised Controlled Trial (RCT) is the 'gold standard' in evidence-based medicine, representing the highest levels of evidence
Aspiration pneumonitis, or Mendelson syndrome, is chemically induce inflammation of the lungs as a result of aspiration of gastric contents
Bronchiectasis
Sildenafil: potent selective phosphodiesterase inhibitor; inhibition of cGMP-specific phosphodiesterase -> pulmonary vasodilator
Rifampicin: inhibits DNA-dependent RNA polymerase activity