End-Stage Renal Failure
End-stage renal failure has multiple implications for ICU management
End-stage renal failure has multiple implications for ICU management
Haemoperfusion: Renal replacement therapy (RRT) using an adsorbent cartridge to remove circulating toxins
Hepatorenal Syndrome = profound oliguria and Na+ retention in the setting of severe liver dysfunction (cirrhosis or fulminant liver failure); usually fatal unless liver transplant performed. RRT can prevent advancement of condition
Renal replacement therapy (RRT): Troubleshooting
Urosepsis is a severe infection, distinguishing it from other urinary tract infections including mild pyelonephritis and accounts for ~5% of severe sepsis; whereas UTIs account for ~40% of nosocomial infections
Renal and Urological Toxicity of Chemotherapy: chronic renal failure; acute renal failure; renal tubular dysfunction; haemorrhagic cystitis; dysuria
Continuous renal replacement therapy (CRRT) is the modality most widely used in Australia and New Zealand ICUs. There is no evidence suggesting mortality benefit for one modality over another
Rhabdomyolysis is the breakdown of skeletal muscle fibres with leakage of potentially toxic intracellular contents into the systemic circulation, characterised by elevated plasma creatine kinase, myoglobinuria and risk of renal impairment
Little published data to guide dosing of antibiotics in RRT and the critically ill. therefore we must use first principles and utilize therapeutic drug monitoring if available.
Steps in preventing Continuous Renal Replacement Therapy circuits from clotting
Indications Contraindications: Choose the correct catheter Handy Hints: References and Links
Contrast-induced nephropathy (CIN) is most commonly defined as renal impairment or acute kidney injury occurring within 48 hr of administration of intravascular radiographic contrast material that is not attributable to other causes