Heerfordt syndrome

Description

Heerfordt syndrome: a rare manifestation of sarcoidosis characterized by the presence of fever, facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever

History

• 1909 – Heerfordt
• 1937 – Jan Waldenström

Associated Persons

• Christian Frederick Heerfordt (1871-1953)
• Jan Gösta Waldenström (1906-1996)

Alternative names

• Heerfordt-Waldenström syndrome
• Uveoparotid fever
• Heerfordt–Mylius syndrome
• Waldenström’s uveoparotitis

Controversies

• Did they first describe or popularise or plagiarise?

References

• Heerfordt CF. ‘Über eine “Febris uveo-parotidea subchronica” an der Glandula parotis und der Uvea des Auges lokalisiert und häufug mit Paresen cerebrospinaler Nerven kompliziert. Albrecht von Grafes Archiv für Ophthalmologie. 1909; 70: 254–273.
• Waldenström JG. Some observations on uveoparotitis and allied conditions with special reference to the symptoms from the nervous system. Acta Medica Scandinavica. 1937;91:53-68.
• Denny MC, Fotino AD. The Heerfordt-Waldenström syndrome as an initial presentation of sarcoidosis. Proc (Bayl Univ Med Cent). 2013 Oct;26(4):390-2.
• Koyama T, Ueda H, Togashi K, Umeoka S, Kataoka M, Nagai S. Radiologic manifestations of sarcoidosis in various organs. Radiographics. 2004 Jan-Feb;24(1):87-104. [PMID 14730039]
• Tamme T, Leibur E, Kulla A. Sarcoidosis (Heerfordt syndrome): a case report. Stomatologija. 2007;9(2):61-4
• Fraga et al. Do you know this syndrome? Heerfordt-Waldenström syndrome. An Bras Dermatol. 2017 Jul-Aug; 92(4): 571–572. [PMC5595615]
• Fujiwara K, Furuta Y, Fukuda S. Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis. Case Rep Otolaryngol. 2016;2016:3642735. [PMC4739221]