Joseph G. Asherman (1889 – 1968) was a Czech-Israeli gynaecologist.
Former director of the Hadassah Municipal Maternity Hospital, Tel Aviv and prominent in the introduction of early post-partum mobilisation and commencement of the surgical management of vesicovaginal fistula.
Asherman was also responsible for introducing welfare centres for impoverished pregnant women and their children. He is eponymously remembered for a series of papers describe the frequency, aetiology, and symptoms of post-traumatic intrauterine adhesions also known as Asherman syndrome
- Born on September 11, 1889 in Rosovice, Czechoslovakia
- 1913 – MD, Prague University
- 1920 – Emigrated to Israel to work in the department of obstetrics and gynaecology of the Hadassah Municipal Maternity Hospital, Tel Aviv.
- 1927 – President of the Israeli Society of Obstetrics and Gynaecology
- Head of the Advisory Council for Preventive Medicine
- Died on October 10, 1968 in Tel Aviv
Asherman Syndrome (1948)
Rare, acquired clinical syndrome presenting with amenorrhoea, menstrual disorders and reproductive dysfunction secondary to intrauterine adhesions. [aka Fritsch syndrome; uterine atresia; amenorrhea traumatica; endometrial sclerosis; intrauterine adhesions; intrauterine synechiae]
In 1948 Asherman described 29 cases he termed ‘amenorrhea traumatica‘ treated between 1944 and 1946, in the Journal of Obstetrics and Gynecology of the British Empire. He acknowledged the work of Stamer and their previous case reports.
This pathological reaction of the uterus is the outcome of a graver injury than usual, such as repeated or deep curettage for missed abortion…or as a result of a normal or even very slight injury when the uterus has been harmed by large-scale haemorrhageAsherman 1948
Asherman’s cases suffered obliteration of the endometrial cavity with amenorrhea ranging from 3-12 months. Treatment involved the passage of a uterine sound through the internal os and dilatation which restored some degree of menstruation in 27/29 cases, with 10 achieving subsequent pregnancy. Asherman initially felt that the stenosis was due to muscular contraction
In our opinion, under certain conditions, the uterus reacts to curettage by tetanic contractions, which may pass after a few moments or hours, but may also continue so long as to become permanent. The contraction of the circular muscles round the uterine os, causes the os to narrow at the close of any abrasion. In the cases under consideration here, prolonged spastic stricture becomes organic in the course of time.Asherman 1948
1950 – Asherman followed his original article with a description of ‘traumatic intrauterine adhesions.’ Asherman collected 65 cases between 1848-1850, evaluated by hysterosalpingography. He presented evidence that curettage or packing of the post-termination or postpartum uterus could induce formation of synechiae within the body of the uterus and advocated hysterotomy, hysteroscopy and digital breakdown of the adhesions as treatment.
Also, hysteroscopy, which has so often been mentioned in the literature and just as often discarded, may perhaps be of use for this purpose. If it were possible to see the adhesions and to loosen them instrumentally, using the eye as a guide, the ideal method would have been foundAsherman 1950
1988 – The American Fertility Society developed an objective scoring system for classification of intrauterine adhesions that correlated the menstrual history with hysteroscopic and hysterosalpingographic findings
- Asherman JG. Amenorrhoea traumatica (atretica). The Journal of Obstetrics and Gynæcology of the British Empire 1948; 55: 23–30.
- Asherman JG. Traumatic intra-uterine adhesions. The Journal of Obstetrics and Gynæcology of the British Empire 1950; 57: 892–6.
- Asherman JG. X-ray therapy in menstrual disorders and infertility. Harefuah. 1957 Apr 1;52(7):163-6.
- Asherman JG. The myth of tubal and endometrial transplantation. J Obstet Gynaecol Br Emp. 1960 Apr;67:228-33.
- Asherman JG. Statistics on maternal mortality. J Int Fed Gynaecol Obstet. 1967 Jul;5(3):211-4.
- Baskett TF. Asherman, Joseph (1889–1968). In: Eponyms and Names in Obstetrics and Gynaecology. 3e. 2019: 10-11
- Fritsch H. Ein Fall von volligem Schwaund der Gebormutterhohle nach Auskratzung [A case of complete disappearance of the uterine cavity after extraction]. Zentralblatt für Gynäkologie. 1894; 18: 52–54.
- Bass B. Ueber die Verwachsungen in der cervix uterinach curettagen. Zentralblatt für Gynäkologie 1927; 51: 223.
- Stamer S. Partial and total atresia of the uterus after excochleation. Acta Obstet Gynecol Scand 1946; 26(2): 263-297.
- Topkins PT. Traumatic intrauterine synechiae. The Asherman syndrome. Am J Obstet Gynecol. 1962 Jun 15;83:1599-608.
- The American Fertility Society classifications of adnexal adhesions, distal tubal occlusion, tubal occlusion secondary to tubal ligation, tubal pregnancies, müllerian anomalies and intrauterine adhesions. Fertil Steril. 1988 Jun;49(6):944-55.
- Nasr AL, Al-Inany HG, Thabet SM, Aboulghar M. A clinicohysteroscopic scoring system of intrauterine adhesions. Gynecol Obstet Invest. 2000;50(3):178-81.
- Berman JM. Intrauterine adhesions. Semin Reprod Med. 2008 Jul;26(4):349-55.
- Yu D, Wong YM, Cheong Y, Xia E, Li TC. Asherman syndrome–one century later. Fertil Steril. 2008 Apr;89(4):759-79
the person behind the name
Graduated from Leeds University in 2014 with MBChB and BSC in Primary Care. Qualified as a General Practitioner under RCGP in 2020. Currently working as an Emergency Department doctor in Sir Charles Gairdner Hospital in Perth, Australia.
Associate Professor Curtin Medical School, Curtin University. Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM Sir Charles Gairdner Hospital. Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |