Łucja Frey-Gottesman (1889 – 1942) was a Polish physician and neurologist.
In 1923, Frey published the case of a 25-year-old man who, after a gunshot wound to the left mandible, developed flushing – Le Syndrome du Nerf Auriculo-Temporal – the first complete description of the anatomy, pathology, and potential treatments of gustatory sweating, and later recognised as “Frey syndrome”.
Frey published a total of 43 articles during her short career including papers on spinal cord disorders, brain topography, hereditary conditions of the nervous system.
Her life and career was tragically cut short as she became a victim of the Holocaust during world war two.
- Born 3 November 1889 in Lvóv (part of the Austro-Hungarian empire) (now Lviv, Ukraine)
- 1923 – Graduated medicine from Warsaw University
- 1923-1928 Assistant of Professor Kazimierz Orzechowsky at Lwów, and the neurological clinic of the Warsaw
- 1929 – Returned to Lviv to work at the Jewish Community hospital; Married Marek Gottesman and had two children
- 1941 – Forced by the German army, along with her family and 136000 of the Jewish community, to live in the the Lemberg Ghetto. Here she continued work as a doctor at the Lvóv Ghetto Polyclinic.
- 1942 – On August 20 four hundred people at the Polyclinic, staff and patients included, were killed by German forces; it is believed that she was murdered at this time, or after being deported to Belzec death camp.
Frey syndrome (1923)
Following injury of the auriculotemporal nerve (as a late complication of parotid gland surgery; or gunshot injury in the case of Frey’s patient), inappropriate regeneration may result in gustatory sweating (Frey syndrome). [aka *auriculotemporal syndrome; unilateral gustatory hyperhidrosis; ]
The eponymous term ‘Frey syndrome’ was introduced by Bassoe in 1932. Various alternate eponyms terms exist in recognition of earlier descriptions including: Baillarger syndrome; Baillarger-Frey syndrome; Duphenix syndrome; and Dupuy syndrome
- Duphenix M. Observations sur les fistules du canal salivaire de Stenon. I. Sur une playe compliquée à la joue ou le canal salivaire fut déchiré. Mémoires de l’Académie royale de chirurgie, 1757; III: 431-439.
- Dupuy LE. Sur l’enèvement des ganglions gutturaux des nerfs trisplanchniques sur des chevaux. Journal de médecine, de chirurgie et de pharmacologie. 1816; 37: 340-350.
- Baillarger JGF. Mémoire sur l’obliteration du canal du Sténon. Gazette médicale de Paris, 1853; 23: 194-197.
- Frey L. Przypadek zespoulu nerwu usznoskroniowego. Polska Gazeta Lekarska 1923; 41: 708–710.
- Frey L. Le syndrome du nerf auriculo-temporal. Revue Neurologique 1923; II(2): 97-104.
- Moltrecht M, Michel O. The woman behind Frey’s syndrome: the tragic life of Lucja Frey. Laryngoscope. 2004;114(12):2205-2209.
- O’Neill JP, Condron C, Curran A, Walsh A. Lucja Frey–historical relevance and syndrome review. Surgeon. 2008;6(3):178-181.
- Emeryk-Szajewska B. Lucja Frey-Gottesman – discoverer of Frey’s syndrome and her tragic fate. Neurol Neurochir Pol. 2011;45(4):407-412
- Grzybowski A, Sak J. Lucja Frey (1889–1942): life destroyed by the Holocaust–on the 70th anniversary of her death. Clin Dermatol. 2012;30(3):355-359.
- Thomas E, Aziz-Donnelly A, Garcia-Santibanez R. Women in the History of Neuromuscular Medicine. Neuromuscular Disorders. 2019; 29: 698-703
- Who was this woman? United States Holocaust Memorial Museum
- Bibliography. Frey, Łucja. WorldCat Identities
- Higier S. Das auriculo-temporale Syndrom und seine Pathogenese. Zeitschrift Für Die Gesamte Neurologie Und Psychiatrie, 1926; 106(1): 114–119.
- Bassoe P. The auriculotemporal syndrome and other vasomotor disturbances about the head. Medical Clinics of North America 1932; 16: 405-412
- Motz KM, Kim YJ. Auriculotemporal Syndrome (Frey Syndrome). Otolaryngol Clin North Am. 2016 Apr;49(2):501-9.
the person behind the name