Description

The Markle Sign, Markle Test or Heel Drop Jarring Test is elicited in patients with intraperitoneal inflammation by having a patient stand on his or her toes and suddenly dropping down onto the heels with an audible thump.

If abdominal pain is localised as the heels strike the ground, Markle Sign is positive. If the pain is localised to the right lower quadrant, this is suggestive of acute appendicitis.


In 1973, George Bushar Markle IV (1921-1999) described the test he performed on patients in whom he attempted to localize or rule out the presence of intraperitoneal inflammation. His simple test is performed in the following manner:

The patient is asked to stand knees straight, with or without shoes. The clinician faces him and asks the patient to do as he does. The clinician stands on his toes for a few seconds and, relaxing suddenly, comes down with his full weight upon his heels with a definite thump. The unsuspecting patient does likewise and may be quite surprised to feel a definite pain wherever there is inflammation in the abdomen. Not only can he tell you, usually quite positively, if there is pain, but also he can tell just where the pain is most severe. In the wary patient who bends the knees or who comes down on the heels too gently, it may be necessary to repeat the test with admonitions to the patient not to restrain his short drop

Markle 1973


Clinical Validation

In 1985 Markle published a series of 190 appendectomies, 74% of the patients with acute appendicitis had a positive Markle Sign, with 71% identifying the precise localization of the inflammation. The Markle Sign was shown to be superior to the better known ‘rebound test’ and at least as accurate as the white blood cell count as a diagnostic marker in acute appendicitis.

Markle-Heel-Drop 1985
Markle GB. Heel-Drop Jarring Test for Appendicitis. Arch Surg. 1985

In 2010 Menteş et al evaluated 430 patients with acute abdominal pain and correlated to histological examination of the appendix at operation. They found that the Markle sign had a sensitivity of 85% and specificity of 30%. However a positive Markle sign (heel drop test) AND a WBC > 11.950/mm³; AND presence of pain in the right lower quadrant increased the probability of having appendicitis by 9.75-fold (PPV 96%)

Ahn et al compared the Markle test with rebound tenderness and found the Markle sign had sensitivity of 69% and specificity of 65% in the diagnosis of acute appendicitis, higher than any other marker evaluated in isolation.


Associated Persons

References

Original articles

Review articles


Cite this article as: Michael Leith and Mike Cadogan, "Markle Sign," In: LITFL - Life in the FastLane, Accessed on August 11, 2022, https://litfl.com/markle-sign/.

eponym

the person behind the name

Dr Michael Leith, Emergency Doctor at a tertiary hospital in Perth, Western Australia | LinkedIn |

Associate Professor Curtin Medical School, Curtin University. Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM Sir Charles Gairdner Hospital.  Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

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