Marlis Tolksdorf

Marlis Tolksdorf (1924 – 1997) was a German cytogeneticist.

Eponymously remembered for her description of Wiedemann-Tolksdorf syndrome in 1973

• Born 1924
• Kinderklinik der Universität, Kiel, Germany.
• Christian-Albrechts-Universität zu Kiel
• Abteilung für Allgemeine Pädiatrie, Universität Kiel
• Städtischen Kinderklinik Krefeld tätig
• Died 1997

The credit for our communications on various chromosomopathies is mainly due to Marlies Tolksdorf, with whom I worked for many years. It was she who organized and chaired the 1970 Annual Meeting of the Federal German Human Cytogeneticists, which was held in Kiel

Hans-Rudolf Wiedemann 1992

Medical Eponyms

Wiedemann-Tolksdorf syndrome (1973)

A syndrome of mental retardation, delayed speech development, accelerated growth, peculiar sheep-like facies [Schafsgesicht], and deformities of the fingers and toes.

First described in 1973 by Tolksdorf and Hans-Rudolf Wiedemann (1915-2006), and attributed as eponym by Schönenberg in 1974

Major Publications

• Tolksdorf M, Wiedemann HR, Hansen HG, Lehmann W. Pätau-Syndrom mit Trisomie D 1 und D/D -Translokation [Pätau syndrome with trisomy D 1 and D/D translocation]. Med Welt. 1965;41:2304-2307.
• Bartels H, Kruse K, olksdorf M. Enzymes in Down’s syndrome. Lancet 1968; 291(7546): 820
• Wiedemann HR, Tolksdorf M. Fehlbildungs-Retardierungs-Syndrom mit “Schafsgesicht” und autosomaler Strukturanomalie [An uncommon malformation-retardation syndrome with “sheep-like face” and associated with autosomal structural aberration (author’s transl)]. Klin Padiatr. 1973;185(5):346-351. [Wiedemann-Tolksdorf syndrome]
• Tolksdorf M. The Diagnosis of X-Chromatin by the Leukocyte Test. In: Schwarzacher HG et al. (eds) Methods in Human Cytogenetics. 1974
• Tolksdorf M, Kunze J, Rossius H, Chiyo H. Male infant with cat cry syndrome and apparent absence of the Y chromosome. Eur J Pediatr. 1980;133(3):293-296.
• Tolksdorf M., Wiedemann HR. Clinical Aspects of Down’s Syndrome from Infancy to Adult Life. In: Burgio GR et al (eds) Trisomy 21. Human Genetics Supplement. 1982
• Tolksdorf M. Das Down-Syndrom: Ein Leitfaden für Eltern. 1994
• Partsch C, Pankau R, Sippell WG, Tolksdorf M. Normal growth and normalization of hypergonadotropic hypogonadism in atypical Turner syndrome (45,X/46,XX/47,XXX). 1994 Eur J Pediatr 1994; 153: 451–455

Controversies

• Name: Marlies / Marlis
• DOB/DOD: Orientierung am subjektiven Geschlecht des Hermaphroditen: Praxisempfehlungen in Nachkriegsdeutschland

References

Biography

• Wiedemann HR. Hans-Rudolf Wiedemann in a half century of German pediatric genetics. Am J Med Genet. 1992;43(4):740-746.
• Tolksdorf, Marlis. Universität Kiel
• Marlis Tolksdorf. Semantic Scholar
• Bibliography. Tolksdorf, Marlis. WorldCat Identities

Eponym

• Schönenberg H, Habedank M. Ein neues Fehlbildungs-Retardierungssyndrom (Wiedemann und Tolksdorf) [A new malformation-retardation syndrome (Wiedemann and Tolksdorf) (author’s transl)]. Monatsschr Kinderheilkd. 1974;122(12):900-906.
• Rehder H, Coerdt W, Eggers R. et al. Is there a correlation between morphological and cytogenetic findings in placental tissue from early missed abortions?. Hum Genet 1989; 82, 377–385 (1989). [Dedicated to Professor Marlis Tolksdorf on the occasion of her 65th birthday]