Moschcowitz disease


Congenital syndrome characterised by thrombocytopenia, purpura, haemolytic anaemia, hyaline thromboses, renal failure and neurological symptoms.



1925 – Moschcowitz suspected that a powerful agglutinative and hemolytic poison was responsible for this disease

Associated Persons

Alternative names
  • Thrombotic thrombocytopenic purpura, Thrombotic thrombocytopaenic purpura
  • TTP

  • Did they first describe or popularise or plagiarise?


Original articles

Modern interpretation

  • Marcus AJ. Moschcowitz Revisited. N Engl J Med. 1982 Dec 2;307(23):1447-8.
  • Asada Y, Sumiyoshi A, Hayashi T, Suzumiya J, Kaketani K.Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigen.Thromb Res 1985; 38: 469–79.
  • Hosler GA, Cusumano AM, Hutchins GM. Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome are distinctpathologic entities. A review of 56 autopsy cases. Arch Pathol LabMed 2003; 127: 834–9
  • Lämmle B, Kremer Hovinga JA, Alberio L. Thrombotic thrombocytopenic purpura. J Thromb Haemost. 2005 Aug;3(8):1663-75.
  • Nickson C. Thrombotic thrombocytopenic purpura. CCC

eponymictionary CTA


the names behind the name

Associate Professor Curtin Medical School, Curtin University. Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM Sir Charles Gairdner Hospital.  Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

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