Moschcowitz disease

Description

Congenital syndrome characterised by thrombocytopenia, purpura, haemolytic anaemia, hyaline thromboses, renal failure and neurological symptoms.


History

1924

1925 – Moschcowitz suspected that a powerful agglutinative and hemolytic poison was responsible for this disease


Associated Persons

Alternative names
  • Thrombotic thrombocytopenic purpura, Thrombotic thrombocytopaenic purpura
  • TTP

Controversies
  • Did they first describe or popularise or plagiarise?

References

Original articles

Modern interpretation

  • Marcus AJ. Moschcowitz Revisited. N Engl J Med. 1982 Dec 2;307(23):1447-8.
  • Asada Y, Sumiyoshi A, Hayashi T, Suzumiya J, Kaketani K.Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigen.Thromb Res 1985; 38: 469–79.
  • Hosler GA, Cusumano AM, Hutchins GM. Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome are distinctpathologic entities. A review of 56 autopsy cases. Arch Pathol LabMed 2003; 127: 834–9
  • Lämmle B, Kremer Hovinga JA, Alberio L. Thrombotic thrombocytopenic purpura. J Thromb Haemost. 2005 Aug;3(8):1663-75.
  • Nickson C. Thrombotic thrombocytopenic purpura. CCC

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eponymictionary

the names behind the name

Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM with a passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

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