This is your one stop page for TCA overdose. Find out how to manage the acute overdose and the potential complications. We have also covered the basic TCA pharmacology and a tutorial about sodium channel blockade and the ECG, find out why the QRS will widen.
The non-sedating antihistamines include cetirizine, desloratadine, fexofenadine, levocetirizine and loratadine. In overdose they cause mild CNS depression, in therapeutic and supra therapeutic doses they have been associated with QT prolongation.
The sedating antihistamines include brompheniramine, chlorpheniramine, cyproheptadine, dexchlorpheniramine, dimenhydrinate, diphenhydramine, doxylamine, pheniramine and promethazine
10yr old boy who presented with mild wheeze and shortness of breath. Vitals signs: BP 105/60 RR 20 T 36.4 Sats 99%. Describe and interpret this ECG. LITFL Top 100 ECG
Black Snake antivenom (equine IgG Fab) can be used to treat envenomation from the black snakes in Australia and Papua New Guinea, these include the mulga snake, Butler's mulga snake, Collett's snake, Papuan black snake, red-bellied black snake and the blue-bellied black snake
Brown Snake antivenom (equine IgG Fab) can be used to treat envenomation from the brown snakes in Australia, these include the eastern and western brown snake (gwardar), dugite and other Pseudonaja species
Death Adder antivenom (equine IgG Fab) can be used to treat envenomation from the death adder in Australia and Papua New Guinea.
Tiger Snake antivenom (equine IgG Fab) can be used to treat envenomation from the Tiger snakes in Australia, these include the Common and western Tiger snake, Stephen's banded snake, pale-headed snake, broad-headed snake, rough-scaled snake, copperhead snake and the small-eyed snake
Taipan antivenom (equine IgG Fab) can be used to treat envenomation from the Taipan snakes in Australia and Papua New Guinea, these include the Costal Taipan, Papuan Taipan and the small-scaled or fierce snake
Sea Snake Antivenom (equine IgG Fab) can be used to treat envenomation from all the Sea Snakes found in Australian Waters.
Polyvalent antivenom (equine IgG Fab) is used to treat snake envenomation from Australia and Papua New Guinea snakes. It contains the equivalent of an ampoule of Brown, Tiger, Black, Death and Taipan in 50ml.
Stonefish Antivenom (equine IgG Fab) can be used to treat envenomation from stonefish found in Australian Waters. It may also have a role in the treatment of bull rout, lion fish and cobbler stings.