Selma A. Myhre

Selma Ann (née Myhre) Hageman (1937 – 2012) was an American pediatrician.

During her career Dr Myhre worked with the mentally and developmentally disabled at Western State Hospital in Steilacoom as well as Rainier School in Buckley


Biography
  • Born Selma Ann Myhre on 27 October 1937 in Tacoma, Washington, USA
  • Graduated medicine from the University of Utah Medical School
  • Pediatric residency, University of Washington
  • 1970 – Paul William Hageman, MD (1939-2008)
  • Western State Hospital, Steilacoom
  • Rainier School in Buckley, Washington
  • 1999 – Retired
  • Died 23 November 2012, Puyallup, Washington, USA

Medical Eponyms
Myhre syndrome (1981)

Myhre syndrome (MYHRS) is caused by heterozygous mutation in the SMAD4 gene on chromosome 18q21. Rare sporadic disorder characterized by mental retardation, dysmorphic facial features, including microcephaly, midface hypoplasia, prognathism, and blepharophimosis, typical skeletal anomalies, including short stature, square body shape, broad ribs, iliac hypoplasia, brachydactyly, flattened vertebrae, and thickened calvaria, and cardiovascular defects with a striking fibroproliferative response to surgical intervention. [OMIM #139210][aka Laryngotracheal stenosis, arthropathy, prognathism, and short stature; LAPS syndrome; Growth mental deficiency syndrome of Myhre]

The purpose of this report is to describe two unrelated male subjects with similar dysmorphic features, which we believe represent a syndrome not previously recognized. The cardinal clinical features, summarized in Table 1, were mental retardation, growth deficiency, unusual facies, hearing loss, generalized muscular hypertrophy, joint limitations and skeletal findings…Older paternal age has been documented in these two cases.

Myhre 1981
Myhre syndrome (1981)
Table 1 Features of the disorder found in both patients

Major Publications

References

eponymictionary CTA

eponym

the person behind the name

Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM with a passion for rugby; medical history; medical education; and informatics. Asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | vocortex |

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.