Tag γ-glutamyl cycle
CCC Critical Care compendium 340

Pyroglutamic Acidosis

Pyroglutamic acidosis is a rare cause of high anion gap metabolic acidosis (HAGMA). When glutathione levels are low, the activity of γ-glutamyl cyclotransferase is increased, resulting in pyroglutamic acid accumulation in glutathione-depleted states
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Staph Sepsis Acidosis

You are asked to review a 73 year old lady who is in hospital for treatment of septic arthritis affecting a prosthetic right hip joint inserted 5 years earlier.