Large-scale clinical trials are expensive and take years to go. Do they generate patient and economic benefit that justifies the cost of trials?
Funtabulously Frivolous Friday Five 146 - Just when you thought your brain could unwind on a Friday, some medical trivia FFFF.
An adaptive clinical trial involves a study design in which key characteristics are adjusted while enrollment in the trial is ongoing using prospectively defined decision rules and in response to information arising from the data accumulating in the trial
Broad overview of the complicated process of conducting a clinical trial. Conducting a clinical trial can be conceptualised as having 14 key steps
Clinicians must be able to critically appraise clinical trials to determine their internal validity. Trials should adhere to the CONSORT statement (CONsolidated Standards of Reporting Trials)
In part one of a series on clinical trials, David Denman discusses CONSORT diagrams and the CONSORT statement using the DECRA trial as an example.