Tag clozapine
Toxicology-Library-Toxicant-Drug-340-256

Clozapine toxicity

Clozapine is an atypical antipsychotic, due to its restricted use an acute overdose is a rare event but clinicians should be aware that coma can occur and management is with supportive care. In chronic toxicity agranulocytosis and myocarditis can occur, these are not features of an acute poisoning but monitored in patients with long term therapeutic use.
Toxicology-Conundrum-340 256

Seizures, Sedation and Saliva

A 21-year-old male with a background of schizophrenia and previous intentional overdose, weighing 70kg, was brought to the ED via ambulance after having a witnessed seizure at home.