Tag Cocaine
Carl (Karl) Koller (1857-1944) 680

Carl Koller

Carl (Karl) Koller (1857–1944), Austrian ophthalmologist who introduced cocaine as the first practical local anaesthetic in 1884, transforming surgery and enabling regional and neuraxial anaesthesia.

William Stewart Halsted (1852-1922) 680

William Halsted

William Halsted (1852–1922), pioneering American surgeon, revolutionized surgery with aseptic technique, anesthesia, gloves, and the residency training model.

Toxicology-Library-Toxicant-Drug-340-256

Cocaine toxicity

Cocaine is a classic sympathomimetic, used by the Incas as an appetite suppressant and noted for its analgesic properties we now use it medically as a local anaesthetic (Sodium channel blockade of the nerves).

CCC Critical Care compendium 340

Cocaine-related Chest Pain

Cocaine is a recreational drug with sympathomimetic effects in additional to being a sodium channel blocker. Cocaine can induce acute coronary syndromes through vasoconstriction, atheroma rupture and/ or dissection

CCC Critical Care compendium 340

Cocaine Toxicity

Cocaine Toxicity potentially life-threatening sympathomimetic syndrome with sodium channel blockade.