Funtabulously Frivolous Friday Five 328 - Just when you thought your brain could unwind, enter the medical trivia of FFFF.
ACEM Primary Pharmacology of Colchicine: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects
Colchicine toxicity is rare but any intention overdose with colchicine is potentially lethal. Although resuscitation is a priority as with all toxicities, colchicine requires urgent decontamination due to the limited therapies we have once toxic serum levels develop.
A 20 year-old female had a polypharmacy overdose 36 hours ago. She has had symptoms of GI upset (nausea and vomiting), some anxiety and mild confusion. Her life is in your hands...