The Cabot-Locke murmur is an early diastolic murmur found in patients with severe anaemia. The murmur resolves with treatment of the anaemia. There is no functional valvular abnormality present.
Richard Clarke Cabot (1868-1939) American physician - clinical haematology; pioneering approach to social work; Cabot-Locke murmur (1903)
Edwin Allen Locke (1874-1971) was an American Physician involved care and treatment of TB and pulmonary disease. Eponym: Cabot-Locke murmur (1903)