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Home | LITFL | Eponymictionary | Cabot-Locke murmur

Cabot-Locke murmur

by Dr Mike Cadogan, last update October 14, 2018

Description

The Cabot-Locke murmur is an early diastolic murmur found in patients with severe anaemia. The murmur resolves with treatment of the anaemia. There is no functional valvular abnormality present.

Umlike the early diastolic murmur assoicated with aortic regurgitation, the Cabot-Locke murmur has no associated ‘decrescendo’ phase.

Note: The description of the Cabot-Locke murmur was based on a study sample of three patients…


Associated Persons

  • Richard Clarke Cabot (1868- 1939)
  • Edwin Allen Locke (1874-1971)

References

  • Cabot RC, Locke EA. On the occurrence of diastolic murmurs without lesions of the aortic or pulmonary valves. Bull Johns Hopkins Hosp 1903;14:115-20.
  • Ma I, Tierney LM. Name that murmur–eponyms for the astute auscultician. N Engl J Med. 2010 Nov 25;363(22):2164-8.[PMID 21105801]

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About Dr Mike Cadogan

Emergency physician with a passion for medical informatics and medical education/textbooks. Asynchronous learning #FOAMed evangelist. | @sandnsurf | + Mike Cadogan | LinkedIn

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