ACEM Primary Pharmacology of Ketamine: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects
Ketamine: phencyclidine derivative hypnotic and analgesic. NMDA receptor antagonist resulting in dissociative anaesthesia (profound analgesia with superficial sleep); interacts with opioid receptors - mu, delta and kappa
Traditionally ketamine was contra-indicated for use in rapid sequence intubation of the head injured patient. This view has since been debunked. Recent evidence suggests that ketamine may actually be useful in this setting
A Question and Answer review of Paediatric Sedation In The Emergency Department. Ketamine and ketamine sedation
A case-based Q-and-A on procedural sedation using ketamine to remove a button battery from a child's nose. What if laryngospasm occurs?