ACEM Primary Pharmacology of Octreotide: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects
Long-acting synthetic octapeptide analogue of somatostatin useful in the control of sulfonylurea-induced hypoglycaemia (BSL <4 mol/L) either from overdose or an iatrogenic source. It is also useful in hypoglycaemia induced from Quinine.
Octreotide: somatostatin analogue; reduces portal hypertension; antidote to sulfonylureas; reduces GI secretions
the case. A 48 year old female arrives to ED via ambulance following an intentional overdose. Her husband discovered her taking tablet after tablet in the bathroom at home. She has a history of depression & diabetes and reports feeling…