ACEM Primary Pharmacology of Theophylline: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects
Theophylline has a narrow therapeutic index, both acute and chronic overdose is potentially life-threatening requiring aggressive supportive care and dialysis to ensure a good outcome
A small child has swallowed two unknown tablets. How would you manage this problem in the emergency department?
Toxicological evaluation and treatment of a patient with theophylline toxicity
Theophylline and caffeine are the most commonly encountered methylxanthines. Theophylline = water soluble aminophylline derivative; cAMP phosphodiesterase inhibitors