Adie syndrome

Description

Holmes-Adie syndrome (aka Adie syndrome) affects the autonomic nervous system. Patients present with the pupil of one eye being larger and only slowly constricts in bright light (tonic pupil). There is also absence of deep tendon reflexes, usually the Achilles tendon.


History

1812 – James Ware described some features in his dissertation on Observations relative to the near and distant sight of different persons read November 1812, published 1813

1881 – John Hughlings Jackson described the syndrome in full [1881: 1: 139-154.]

1902 – Julius Strasberger, Alfred Saenger and Max Nonne further described and defined the pupillary findings.

1914 – H. Oloff determined that the condition was not syphilitic in origin

1926 – Weill and Reys summarised the condition completely

1931William John Adie recognised the work of his colleagues including Foster Moore (described 15 such cases 1924-1931) who later expressed his ‘dissatisfaction’ at not having been ascribed the eponym…

1931Gordon Morgan Holmes described 19 patients with the condition

1934Jean-Alexandre Barré first used the term ‘syndrome d’Adie


Associated Persons


Alternative names

  • Adie pupil
  • Adie-Holmes syndrome
  • Holmes-Adie syndrome
  • Weill-Reys syndrome

References


eponymictionary CTA 2

eponymictionary

medical etymology

Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM with a passion for rugby; medical history; medical education; and informatics. Asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | vocortex |

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