Anne P. Forbes
Anne Pappenheimer Forbes (1911 – 1992) was an American endocrinologist and physician.
Following house staff training at Johns Hopkins Hospital, Dr. Forbes moved to Massachusetts General Hospital where she helped to establish the Ovarian Dysfunction Clinic. She then relocated to Harvard Medical School, where she eventually became clinical professor of medicine emeritus. Here, she worked with Dr. Fuller Albright and participated in the identification of many diseases, including Forbes-Albright Syndrome, a pituitary gland disorder.
Dr. Forbes served as assistant professor of medicine at the Pahlavi University Medical School in Shiraz, Iran, from 1967 to 1969.
Biography
- 1911 – Born Anne Pappenheimer on November 11, in New York City
- 1932 – BA, Radcliffe College
- 1935 – Married William H. Forbes (1903-1995) on the 31st December, Bronx, New York. Five children (three daughters, two sons)
- 1936 – Graduated medicine, College of Physicians and Surgeons, Columbia University
- 1936-1938 – Interned at Johns Hopkins Hospital
- 1938-1948 – Research fellow at Massachusetts General Hospital in the endocrinology lab of Fuller Albright (1900-1969)
- 1962-1967 – Assistant clinical professor of medicine, Harvard medical school
- 1967-1969 – Assistant professor of medicine at the Pahlavi University Medical School in Shiraz, Iran
- 1970-1980 – Associate clinical professor of medicine, Harvard medical school
- 1980 – Retired; took up raising sheep, shearing the wool herself then spinning and dyeing it by hand
- 1992 – Died 25 February
Medical Eponyms
Forbes-Albright syndrome (1954)
A disorder characterized by galactorrhea and amenorrhoea. Three types recognized:
- Chiari-Frommel syndrome: persistent galactorrhoea and amenorrhea after giving birth. [1882]
- Ahumada-Del Castillo syndrome: galactorrhoea-amenorrhoea not associated with pregnancy. There is oestrogen deficiency and decreased urinary gonadotropin levels. [1932, 1953]
- Forbes-Albright syndrome: galactorrhea-amenorrhea caused by a chromophobe prolactin-producing adenoma of the pituitary. [1954]
In 1954, Forbes, Albright and colleagues described 15 non-acromegalic women with persistent amenorrhea-galactorrhea and suggested that these findings were due to hypersecretion of pituitary prolactin. Eight of these patients had enlarged sellae with three chromophobe adenomas surgically demonstrated. The remaining seven had normal sellae.
Major Publications
- Albright F, Forbes AP, Bartter FC. The effect of adrenocorticotrophic hormone in patients with panhypopituitarism. Trans Conf Metab Asp Conval. 1947;60:118-127.
- Forbes PA, Henneman PH, Griswold GC, Albright F. A Syndrome, Distinct from Acromegaly, Characterized by Spontaneous Lactation, Amenorrhea, and Low Follicle-Stimulating Hormone Excretion. The Association for the Study of Internal Secretions; Abstracts of papers presented at the thirty-third annual meeting. The Journal of Clinical Endocrinology & Metabolism, 1951; 11(7): 749.
- Albright F, Forbes AP, Henneman PH. Pseudo-pseudohypoparathyroidism. Trans Assoc Am Physicians. 1952;65:337-350.
- Forbes PA, Henneman PH, Griswold GC, Albright F. Syndrome characterized by galactorrhea, amenorrhea and low urinary FSH: comparison with acromegaly and normal lactation. The Journal of Clinical Endocrinology & Metabolism. 1954;14(3):265-271.
- Forbes AP, Engel E. The high incidence of diabetes mellitus in 41 patients with gonadal dysgenesis, and their close relatives. Metabolism. 1963;12:428-439.
- Forbes AP. Fuller Albright 1900-1969. Harvard medical alumni bulletin 1970; 44(4): 36
- Bode HH, Dorf ME, Forbes AP. Familial lymphocytic thyroiditis: analysis of linkage with histocompatibility and blood groups. The Journal of Clinical Endocrinology & Metabolism. 1973;37(5):692-697.
- Forbes AP. Fuller Albright. His concept of postmenopausal osteoporosis and what came of it. Clin Orthop Relat Res. 1991;(269):128-141.
References
Biography
- Obituary: Dr. Anne Forbes, 80, Endocrinology Pioneer. New York Times Feb 29, 1992
- Portrait. Anne Pappenheimer Forbes, M.D. Harvard Medical Library
- Stethoscope sorority. Anne Pappenheimer Forbes. Center for the history of medicine, Countway Library
- Anne Pappenheimer Forbes: Personal and professional papers 1930-1991. Center for the history of medicine, Countway Library
- Forbes, Anne Pappenheimer. Who’s who of American women. 1973: 306
- Tripp EF. Surviving Iraq : soldiers’ stories. 2008: VIII
Eponymous term
- Frommel R. Über puerperale Atrophie des Uterus. Zeitschrift für Geburtshulfe und Gynäkologie, 1882; 7: 305-313.
- Ahumada JC, del Castillo EB. Sobre in caso de galactorrea y amenorrea. Boletin de la Sociedad de obstetricia y ginecologia de Buenos Aires, 1932; 11: 64-72.
- Argonz J, del Castillo EB. A syndrome characterized by estrogenic insufficiency, galactorrhea and decreased urinary gonadotropin. J Clin Endocrinol Metab. 1953;13(1):79-87.
Graduated from Cardiff Medical School in 2017 with MBBCh and BSc in Psychology and Medicine. Currently working as a doctor in the emergency department at Sir Charles Gairdner Hospital in Perth, Australia.