Hypophosphataemia
Hypophosphataemia: Phosphate - important intracellular anion; 85% is stored in bone as hydroxyapapitie crystals, 14% in soft tissues, 1% in blood
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Hypophosphataemia: Phosphate - important intracellular anion; 85% is stored in bone as hydroxyapapitie crystals, 14% in soft tissues, 1% in blood
Hypokalaemia: the most common electrolyte abnormality in hospitalised patients; mostly caused by drugs and GI disease
Hypocalcaemia: Reduced intake; redistribution and increased output
Hypernatraemia can be caused by a number of critical illnesses: water depletion (decreased intake, hypotonic fluid loss – renal/non-renal); solute excess (Na+ or other)
Hyperkalaemia is a life-threatening emergency. Basic overview of hyperkalemia management
Ca2+ exists in the extracellular plasma two states: (1) free ionized state and (2) bound to other molecules (mostly albumin, rest – beta-globulins, phosphate, citrate)
ionized Ca2+ concentration is inversely related to pH -> an increase in pH results in a decrease in ionized Ca2+
Pseudomembranous colitis (PMC); acute inflammatory disease of colon commonly associated with antibiotic use; C. difficile implicated as a causative organism in 1970’s
Portopulmonary Syndrome is NOT considered contraindication to liver transplantation; affects ~20% of pre-transplant patients; usually due to increased blood flow through the lungs without increased resistance
Cuff pressure gauge aka cuff manometer; allows safe inflation of the cuff seal of low pressure endotracheal and laryngeal tube cuffs by measuring the cuff pressure
GENERAL APPROACH Considerations Transplant – liver, heart, lung, heart-lung, bone marrow, renal, pancreatic Phase of care – immediate post op, sepsis, rejection, respiratory failure, renal failure Surgery – graft function, anatomy, anastomoses (leaks and occlusion) Infection – bacterial (early), opportunistic:…
GENERAL APPROACH Find the shock (is it PROVED?) Pump, rate/ rhythm = Cardiogenic – myocardial, valves, rhythm, pericardium, left and right sided (signs: cool peripherally, shut down, bounding pulse, narrow pulse pressure, inotropes, high CVP, low SvO2, low Q, crackles…
GENERAL APPROACH Type of surgery Emergency or Elective Post-operative complications (bleeding, tamponade, graft occlusion, CVA) Shock assessment Causes and type of heart disease INTRODUCTION CUBICLE short or long term patient tracheostomy organ support INFUSIONS vasoactives haemostatic agents (tranexamic acid, blood…