Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care compendium 340

Rotavirus

Rotavirus is the leading cause of gastroenteritis worldwide and a leading cause of infant death in the developing world. 95% of U.S. children have had a rotavirus infection by the age of 5 years.

CCC Critical Care compendium 340

Peritoneal Fluid Analysis

The peritoneum is a tough semi-permeable membrane lining abdominal and visceral cavities. it encloses, supports and lubricates organs within the cavity. Paracentesis is effectively the analysis of 'Ascites' - the abnormal accumulation of fluid within the abdomen.

CCC Critical Care compendium 340

Quantitative Data Types and Tests

Quantitative data is that which can be expressed numerically and is associated with a measurement scale; not all numbers constitute quantitative data (e.g. tax file number!)

CCC Critical Care compendium 340

Calcium basics

Calcium is the most abundant mineral in the body. 1.5% of body weight; 99% is in bone matrix; 1100gramm (27mmol)

CCC Critical Care compendium 340

Factor VIIa

Tissue factor + VIIa + platelets -> platelet aggregation -> production of platelet-fibrin matrix -> haemostasis; used in massive transfusion senario’s to attempt to control intractable haemorrhage

CCC Critical Care compendium 340

Stress Induced Hyperglycaemia

Stress Induced Hyperglycaemia (SIH) is transient hyperglycaemia associated with acute illness
resolves with resolution of the underlying critical illness

CCC Critical Care compendium 340

Adenosine

Adenosine: short acting anti-arrhythmic; naturally occurring purine nucleoside. Epression of SA & AV nodal activity; antagonises cAMP-mediated catecholamine stimulation of ventricular muscle

CCC Critical Care compendium 340

History of Emergency Medicine

The history of emergency medicine in Australia and New Zealand has paralleled developments in the United States, Canada and the United Kingdom, although the models of emergency care exhibit some variation between systems, and between institutions within these systems

CCC Critical Care compendium 340

Surrogate outcomes

Surrogate outcomes are biomarkers intended to substitute for a clinical endpoint and expected to predict clinical benefit or harm based on epidemiologic, therapeutic, pathophysiologic, or other scientific evidence