- Rotavirus is the leading cause of gastroenteritis worldwide and a leading cause of infant death in the developing world.
- 95% of U.S. children have had a rotavirus infection by the age of 5 years.
- Most cases occur in late winter and early spring.
- Route of transmission is mostly fecal-oral but may be airborne in cooler months.
- fever (1/3 of cases)
- vomiting (in the first 1-2 days)
- diarrhea (copious, watery, lasting 5-21 days)
- usually a clinical diagnosis
- antigen assays useful for surveillance, isolation/ cohorting in hospital and if complications present
- supportive care
- maintain hydration (ORS is the mainstay)
- key to disease control
- good hand hygiene
- vaccination — effective in decreasing hospitalizations and deaths in developing countries.
References and Links
- Cox, Elaine and Christenson, John. Rotavirus. Pediatrics in Review. 2012; 33 (10): 439 – 447.