Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care compendium 340

Drowning

Drowning is the process of experiencing respiratory impairment from submersion/immersion in liquid (WHO 2002 definition)
drowning can be due to — submersion (the airway goes below the level of the surface of the liquid) or — immersion (a liquid is splashed across a person’s face, e.g water-boarding)

CCC Critical Care compendium 340

Anaphylaxis

Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway (pharyngeal or laryngeal edema) and/or breathing (bronchospasm and tachypnea) and/or circulation (hypotension and tachycardia) problems usually associated with skin and mucosal changes

CCC Critical Care compendium 340

Resuscitation Team Leader

The roles and priorities in a cardiac arrest situation is dependent on: the environment where arrest takes place; the nature of the cardiac arrest, ; and the skill mix of the people in the immediate environment

CCC Critical Care compendium 340

Hypovolaemia

DETRIMENTAL EFFECTS Detrimental effects are due to impaired cardiac output and organ perfusion and oxygen delivery oliguria -> ATN -> cortical necrosis -> ARF cerebral ischaemia -> confusion -> decreased LOC -> infarction myocardial ischaemia -> cardiogenic shock -> heart…

CCC Critical Care compendium 340

Immediate Post-ROSC Management

A team-based approach to the management of the post-ROSC patient focuses on initiation of therapeutic hypothermia, treatment of the underlying cause with transfer to the cath lab where appropriate, and management of the post-cardiac arrest syndrome.

CCC Critical Care compendium 340

Deresuscitation and Positive Fluid Balance

Deresuscitation specifically refers to 'Late Goal Directed Fluid Removal (LGFR)', which involves "aggressive and active fluid removal by means of diuretics and renal replacement therapy with net ultrafiltration" (Malbrain et al, 2014)

CCC Critical Care compendium 340

Glycocalyx in Critical Illness

The endothelial glycocalyx (EG) is a thin proteinaceous layer previously thought to be inert, that is now thought to play a key role in vascular integrity and function. The glycocalyx has potential as a novel therapeutic target

CCC Critical Care compendium 340

Chronic Graft Versus Host Disease

Chronic Graft vs Host Disease is organ dysfunction occurring > 100 days post transplantation; distinct clinical syndrome from acute GVHD; pathophysiology poorly understood