
Hypokalaemic Periodic Paralysis
Hypokalaemic Periodic Paralysis; rare channelopathy; muscle weakness/paralysis with a matching fall in K+ levels; starts in adolescence; weakness may be mild -> full body paralysis

Hypokalaemic Periodic Paralysis; rare channelopathy; muscle weakness/paralysis with a matching fall in K+ levels; starts in adolescence; weakness may be mild -> full body paralysis

Leptospirosis is an infection caused by the spirochaete genus of Leptospira. Severe forms may result in critical illness, including Weil disease and severe pulmonary haemorrhage

GENERAL APPROACH INTRODUCTION CUBICLE INFUSIONS VENTILATOR MONITOR EQUIPMENT QUESTION SPECIFIC EXAMINATION -> scars, surgical wounds, drains-> motor level: myotomes, spinal reflexes, limbs and abdominal muscles, return of bulbocaveronsus reflex (resolution of spinal shock)-> sensory level: dermatomes, sensory tracts (dorsal columns,…

GENERAL APPROACH Illness requiring ICU admission Pregnancy + Baby Delivery – when or already done INTRODUCTION CUBICLE CTG presence of midwives INFUSIONS PET: MgSO4, phenytoin, hydralazine, GTN pre-term labour: tocolytics, steroids thromboembolism: heparin bleeding: blood products, fluid boluses, TXA cardiogenic…

Hepatic veno-occlusive disease aka sinusoidal obstruction syndrome (SOS) important complication of stem cell transplantation (SCT) mortality >30%

Haemophagocytic lymphohistiocytosis (HLH) may be inherited (AR; 5 subtypes, aka familial HLH) or acquired; may mimic severe sepsis, consider in apparent sepsis without source

Cryoprecipitate is prepared by thawing fresh frozen plasma (FFP) between 1°C and 6°C and recovering the precipitate
The cold-insoluble precipitate is refrozen.

Reviewed and revised 10 March 2014 OVERVIEW Massive transfusion is defined as A Massive Transfusion Protocol should be used in critically bleeding patients anticipated to require massive transfusion GOALS IN MANAGEMENT OF MASSIVE TRANSFUSION THERAPY INDICATIONS IN MASSIVE TRANSFUSION MASSIVE TRANSFUSION…

Acute or ascending cholangitis is a potentially life-threatening systemic infection resulting from inflammation and infection of the biliary tree due to bacterial growth in the bile, usually in the context of biliary obstruction

Antibacterial Resistance: Natural Resistance – they do not possess the molecular target of the drug or are impermeable to it; Acquired resistance – occurs through mutation or the acquisition of new genetic material carried by mobile elements

Antimicrobial Quick Reference

Antimicrobial Stewardship is defined as ‘an ongoing effort by a health-care institution to optimise antimicrobial use among hospital patients in order to improve patient outcomes, ensure cost-effective therapy and reduce adverse sequelae of antimicrobial use (including antimicrobial resistance)’